产品货号：
Z12726
中文名称：
Caspase 8/CASP8抗体
英文名称：
Anti-Caspase 8/CASP8 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Caspase 8/CASP8 Antibody |
| 指标别名 | Apoptotic protease Mch 5;Casp 8;CASP8;Caspase 8;Caspase 8/p18;Caspase 8/p43/p18;caspase8;FADD like ICE;FLICE;ICE like apoptotic protease 5;MCH5 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,ICC,IF |
| 基因名称 | CASP8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Caspase-8 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Caspase-8 isoform A.The immunogen is located within the last 50 amino acids of Caspase-8. |
| 计算分子量 | 55kDa |
| 成分 | Caspase-8 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Caspase-8 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Caspase-8 antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies.Unlike the apoptotic caspases,members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens.The apoptotic subfamily can be further divided into initiator caspases,which are activated in response to death signals,and executioner caspases,which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death.Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex.The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain;subsequent oligomerization promotes procaspase-8 autoactivation.FLIP,a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis. |
| Uniprot ID | Q14790 |
| 基因名全称 | Caspase 8,apoptosis-related cysteine peptidase |
| 蛋白名全称 | Caspase 8,apoptosis-related cysteine peptidase |
| 推荐稀释比 | Caspase-8 antibody can be used for the detection of caspase-8 by Western blot at 0.5 to 2μg/mL.Antibody can also be used for immunocytochemistry starting at 2μg/mL and immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human,mouse,and rat samples;Immunohistochemistry in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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